{"id":169,"date":"2023-08-24T23:56:37","date_gmt":"2023-08-24T23:56:37","guid":{"rendered":"https:\/\/pharmacosmosmedical.com\/staging\/1978\/?page_id=169"},"modified":"2026-03-30T09:57:23","modified_gmt":"2026-03-30T09:57:23","slug":"phosphare-clinical-trials","status":"publish","type":"page","link":"https:\/\/pharmacosmosmedical.com\/staging\/1978\/phosphare-clinical-trials\/","title":{"rendered":"PHOSPHARE Clinical Trials"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Course Hero&#8221; _builder_version=&#8221;4.23.3&#8243; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_stops=&#8221;#131b68 0%|#9271f6 100%&#8221; background_color_gradient_start=&#8221;#474ab6&#8243; background_color_gradient_end=&#8221;#9271f6&#8243; background_image=&#8221;https:\/\/pharmacosmosmedical.com\/staging\/1978\/wp-content\/uploads\/2023\/07\/coding-background-texture.jpg&#8221; background_blend=&#8221;overlay&#8221; custom_padding=&#8221;35px|0px|0px|0px|false|false&#8221; animation_style=&#8221;slide&#8221; animation_direction=&#8221;top&#8221; animation_intensity_slide=&#8221;2%&#8221; da_disable_devices=&#8221;off|off|off&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; min_height=&#8221;208.5px&#8221; custom_padding=&#8221;27px|0px|24px|0px&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.23.1&#8243; header_font=&#8221;|on|||&#8221; header_text_align=&#8221;center&#8221; header_font_size=&#8221;42px&#8221; header_line_height=&#8221;1.3em&#8221; background_layout=&#8221;dark&#8221; custom_padding=&#8221;|||&#8221; header_font_size_tablet=&#8221;&#8221; header_font_size_phone=&#8221;&#8221; header_font_size_last_edited=&#8221;on|desktop&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1>PHOSPHARE Clinical Trials<\/h1>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.23.1&#8243; text_text_color=&#8221;#d4ccff&#8221; text_font_size=&#8221;16px&#8221; text_orientation=&#8221;center&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Hypophosphatemia has emerged as a side effect of some newer intravenous (IV) iron products. While some incidents can be resolved transiently, complications can occur based on the severity of hypophosphatemia and the time to recover. The PHOSPHARE-IDA trials are two identically-designed, clinical studies that evaluated the risks of hypophosphatemia with two different IV irons. Additional analyses from these data and similar studies were performed.<\/p>\n<p>This section includes links to Pharmacosmos sponsored-publications and selected Pharmacosmos posters. Information contained in these publications may include information that is inconsistent with the FDA approved use of product(s). Pharmacosmos does not recommend the use of its products in a manner that is inconsistent with FDA-approved labeling. Additionally, t<span>he content contained in this section is subject to congress copyright permissions.<\/span><\/p>\n<p><span><\/span><\/p>\n<p><span><\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;Features&#8221; _builder_version=&#8221;4.16&#8243; custom_margin=&#8221;|||&#8221; custom_padding=&#8221;40px|0px|98px|0px||&#8221; da_disable_devices=&#8221;off|off|off&#8221; global_colors_info=&#8221;{}&#8221; da_is_popup=&#8221;off&#8221; da_exit_intent=&#8221;off&#8221; da_has_close=&#8221;on&#8221; da_alt_close=&#8221;off&#8221; da_dark_close=&#8221;off&#8221; da_not_modal=&#8221;on&#8221; da_is_singular=&#8221;off&#8221; da_with_loader=&#8221;off&#8221; da_has_shadow=&#8221;on&#8221;][et_pb_row column_structure=&#8221;1_3,1_3,1_3&#8243; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.27.4&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; custom_padding=&#8221;||||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.23.3&#8243; custom_padding=&#8221;|||&#8221; box_shadow_style=&#8221;preset1&#8243; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb _builder_version=&#8221;4.27.4&#8243; body_text_color=&#8221;#131B68&#8243; body_font_size=&#8221;16px&#8221; body_line_height=&#8221;1.5em&#8221; custom_margin=&#8221;||42px||false|false&#8221; custom_margin_tablet=&#8221;||0px||false|false&#8221; custom_margin_phone=&#8221;||0px||false|false&#8221; custom_margin_last_edited=&#8221;on|tablet&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; custom_margin__hover_enabled=&#8221;off|desktop&#8221;]<\/p>\n<p>April 2023 I Gut<\/p>\n<p><strong>Hypophosphatemia following ferric derisomaltose and ferric carboxymaltose in patients with iron deficiency anaemia due to inflammatory bowel disease (PHOSPHARE-IBD): a randomised clinical trial<\/strong><\/p>\n<p>Zoller H, Wolf M, Blumenstein I, et al.<\/p>\n<p>[\/et_pb_blurb][et_pb_blurb icon_placement=&#8221;left&#8221; _builder_version=&#8221;4.27.4&#8243; header_font=&#8221;|on|||&#8221; header_text_color=&#8221;#2e2545&#8243; header_line_height=&#8221;1.5em&#8221; body_text_color=&#8221;#131B68&#8243; background_color=&#8221;#ffffff&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; custom_margin=&#8221;||||false|false&#8221; custom_padding=&#8221;|20px|20px|20px|false|true&#8221; animation_style=&#8221;zoom&#8221; animation_direction=&#8221;left&#8221; animation_intensity_zoom=&#8221;10%&#8221; animation_starting_opacity=&#8221;100%&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: center;\"><strong>\u00a0<a href=\"#pop-4\" target=\"_blank\" rel=\"noopener\">View Publication<\/a><\/strong><\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.23.3&#8243; custom_padding=&#8221;|||&#8221; box_shadow_style=&#8221;preset1&#8243; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb _builder_version=&#8221;4.27.4&#8243; body_text_color=&#8221;#131B68&#8243; body_font_size=&#8221;16px&#8221; body_line_height=&#8221;1.5em&#8221; custom_margin=&#8221;||42px||false|false&#8221; custom_margin_tablet=&#8221;||0px||false|false&#8221; custom_margin_phone=&#8221;||0px||false|false&#8221; custom_margin_last_edited=&#8221;on|tablet&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>March 2022 I J Clin Endocrinol Metab<\/p>\n<p><strong>Risk factors for and effects of persistent and severe hypophosphatemia following ferric carboxymaltose<\/strong><\/p>\n<p>Schaefer B, Zoller H, Wolf M, et al.<\/p>\n<p>[\/et_pb_blurb][et_pb_blurb icon_placement=&#8221;left&#8221; _builder_version=&#8221;4.27.4&#8243; header_font=&#8221;|on|||&#8221; header_text_color=&#8221;#2e2545&#8243; header_line_height=&#8221;1.5em&#8221; body_text_color=&#8221;#131b68&#8243; background_color=&#8221;#ffffff&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; custom_margin=&#8221;0px||0px||false|false&#8221; custom_margin_tablet=&#8221;0px||0px||false|false&#8221; custom_margin_phone=&#8221;0px||0px||false|false&#8221; custom_margin_last_edited=&#8221;on|tablet&#8221; custom_padding=&#8221;11px|20px|20px|20px|false|true&#8221; custom_padding_tablet=&#8221;0px|20px|20px|20px|false|true&#8221; custom_padding_phone=&#8221;0px||||false|true&#8221; custom_padding_last_edited=&#8221;on|tablet&#8221; animation_style=&#8221;zoom&#8221; animation_direction=&#8221;left&#8221; animation_intensity_zoom=&#8221;10%&#8221; animation_starting_opacity=&#8221;100%&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: center;\"><strong><\/strong><\/p>\n<p style=\"text-align: center;\"><strong><\/strong><\/p>\n<p style=\"text-align: center;\"><strong><\/strong><\/p>\n<p style=\"text-align: center;\"><strong><\/strong><\/p>\n<p style=\"text-align: center;\"><a href=\"#pop-3\" target=\"_blank\" rel=\"noopener\"><strong>View Publication<\/strong><\/a><\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.23.3&#8243; custom_padding=&#8221;|||&#8221; box_shadow_style=&#8221;preset1&#8243; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb _builder_version=&#8221;4.27.4&#8243; body_text_color=&#8221;#131B68&#8243; body_font_size=&#8221;16px&#8221; body_line_height=&#8221;1.5em&#8221; custom_margin=&#8221;||42px||false|false&#8221; custom_margin_tablet=&#8221;||0px||false|false&#8221; custom_margin_phone=&#8221;||0px||false|false&#8221; custom_margin_last_edited=&#8221;on|tablet&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>February 2020 I JAMA<br \/><strong><\/strong><\/p>\n<p><strong>Effects of iron isomaltoside vs ferric carboxymaltose on hypophosphatemia in iron-deficiency anemia<\/strong><\/p>\n<p>Wolf M, Rubin J, Achebe M, et al.<\/p>\n<p>[\/et_pb_blurb][et_pb_blurb icon_placement=&#8221;left&#8221; _builder_version=&#8221;4.27.4&#8243; header_font=&#8221;|on|||&#8221; header_text_color=&#8221;#2e2545&#8243; header_line_height=&#8221;1.5em&#8221; body_text_color=&#8221;#131b68&#8243; background_color=&#8221;#ffffff&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; width=&#8221;100%&#8221; custom_margin=&#8221;||||false|false&#8221; custom_padding=&#8221;40px|20px|20px|20px|false|true&#8221; custom_padding_tablet=&#8221;0px|20px|20px|20px|false|true&#8221; custom_padding_phone=&#8221;0px|20px|20px|20px|false|true&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; animation_style=&#8221;zoom&#8221; animation_direction=&#8221;left&#8221; animation_intensity_zoom=&#8221;10%&#8221; animation_starting_opacity=&#8221;100%&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: center;\">\n<p style=\"text-align: center;\">\n<p style=\"text-align: center;\"><a href=\"#pop\" target=\"_blank\" rel=\"noopener\"><strong>View Publication<\/strong><\/a><\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_3,1_3,1_3&#8243; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.27.4&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; custom_padding=&#8221;||||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.23.3&#8243; custom_padding=&#8221;|||&#8221; box_shadow_style=&#8221;preset1&#8243; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_blurb _builder_version=&#8221;4.27.4&#8243; body_text_color=&#8221;#131B68&#8243; body_font_size=&#8221;16px&#8221; body_line_height=&#8221;1.5em&#8221; custom_margin=&#8221;||20px||false|false&#8221; custom_margin_tablet=&#8221;||0px||false|false&#8221; custom_margin_phone=&#8221;||0px||false|false&#8221; custom_margin_last_edited=&#8221;on|tablet&#8221; custom_padding=&#8221;20px|20px|20px|20px|true|true&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p style=\"text-align: left;\">April 2019 I Poster Presented at the 20th Annual NATA Symposium (Poster)<\/p>\n<p><strong>Pooled analysis of the PHOSPHARE-IDA 04\/05 studies: findings relevant to respiratory muscle function<\/strong><\/p>\n<p>Zoller H, Schaffalitzky de Muckadell P, Wolf M, et al.<\/p>\n<p>[\/et_pb_blurb][et_pb_blurb icon_placement=&#8221;left&#8221; _builder_version=&#8221;4.27.4&#8243; header_font=&#8221;|on|||&#8221; header_text_color=&#8221;#2e2545&#8243; header_line_height=&#8221;1.5em&#8221; body_text_color=&#8221;#131B68&#8243; background_color=&#8221;#ffffff&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; width=&#8221;100%&#8221; custom_margin=&#8221;28px||-4px||false|false&#8221; custom_margin_tablet=&#8221;0px||-4px||false|false&#8221; custom_margin_phone=&#8221;0px||-4px||false|false&#8221; custom_margin_last_edited=&#8221;on|tablet&#8221; custom_padding=&#8221;17px|20px|26px|20px|false|true&#8221; custom_padding_tablet=&#8221;0px|20px|20px|20px|false|true&#8221; custom_padding_phone=&#8221;0px||||false|true&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; animation_style=&#8221;zoom&#8221; animation_direction=&#8221;left&#8221; animation_intensity_zoom=&#8221;10%&#8221; animation_starting_opacity=&#8221;100%&#8221; locked=&#8221;off&#8221; 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While some incidents can be resolved transiently, complications can occur based on the severity of hypophosphatemia and the time to recover. The PHOSPHARE-IDA trials are two identically-designed, clinical studies that evaluated the risks of hypophosphatemia with two different IV [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"nf_dc_page":"","_et_pb_use_builder":"on","_et_pb_old_content":"<!-- wp:divi\/placeholder \/-->","_et_gb_content_width":"","footnotes":""},"class_list":["post-169","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>PHOSPHARE Clinical Trials - Pharmacosmos Medical<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pharmacosmosmedical.com\/phosphare-clinical-trials\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"PHOSPHARE Clinical Trials - Pharmacosmos Medical\" \/>\n<meta property=\"og:description\" content=\"PHOSPHARE Clinical TrialsHypophosphatemia has emerged as a side effect of some newer intravenous (IV) iron products. 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